News
PGT Awarded NHS Grant to Fund Pharmacogenetic Study on Patient Response to Breast Cancer Chemotherapy
PGT Awarded NHS Grant to Fund Pharmacogenetic Study on Patient Response to Breast Cancer Chemotherapy
March 10, 2010
Population Genetics technologies (PGT) Ltd, a privately owned company based in Cambridge, UK today announced that it has been awarded a grant from the National Institute for Health Research (NIHR) as part of the Institute’s Invention for Innovation (i4i) Programme.
The i4i Programme provides investment in, and improved identification of, promising healthcare technologies in order to accelerate the development of new healthcare products for the 21st century. The i4i programme funds translational research, extending between basic research and pre-clinical trials, or health technology assessments. (more…)
Common and rare variants in multifactorial susceptibility to common disease
June 10, 2009
In a perspective article published in Nature Genetics, Sir Walter Bodmer and Carolina Bonilla argue that rare variants make a large contribution to the multifactorial inheritance of common diseases. They also point to two areas where studies of rare and common variants can intersect. First, they suggest that common variants might act as modifiers of rare variants, and second that genes for which common variants are identified should be considered candidates for functionally relevant rare variants. They conclude that the availability of highly efficient re-sequencing technology is critical in order to meet the challenge of identifying rare variants in disease versus control populations.
Read more at PubMed Central.
PGT Appoints New VP of Business Development
May 25, 2009
Population Genetics Technologies (PGT) Ltd today announced the appointment of Dr Frank Massam as Vice President of Business Development. The move follows the recent announcement of a £2,000,000 second tranche of Series A funding to further develop and commercialize PGT’s suite of proprietary technologies. (more…)
PGT Secures Final £2,000,000 of Series A Funding
May 20, 2009
Population Genetics technologies (PGT) Ltd, a privately owned company based in Cambridge, UK today announced that it had successfully met the commercial and development milestones set by its principal investors thereby securing its final £2,000,000 of Series A funding. (more…)
Common Genetic Variation and Human Traits in NEJM
April 28, 2009
A commentary from David Goldstein at Duke University provides an interpretation and perspective on how best to interpret and utilise data from recent experiments linking human disease and related traits to genetic variation. The April 23, 2009 publication in the New England Journal of Medicine argues the scientific community needs to build on the common variant data with much more extensive investigation of rare variants.